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amoeba - an irregular blob, mostly transparent, with smaller transparent and yellow blobs inside it

Amoeba – a one-celled organism

All cells have to have some way to get energy from outside themselves, or they will starve to death. The earliest, simplest cells, about 3.5 billion years ago, got their food by drifting around in the ocean until they came to a molecule of protein or another hydrocarbon. Then they let that molecule into the cell through the cell membrane. Many cells still get their food this way today.

But starting around 3 billion years ago some cells used different strategies to get food. Sometimes the different strategies were not helpful, and those cells died. One new strategy helped many cells get more food. These cells bent their cell walls, curving them in and out to make long arms. Then they could encircle the food with their arms and keep it from getting away. Some cells also started to make enzymes inside themselves that could react with bigger molecules, or even other cells. Cells used the enzymes to break down big molecules into small molecules that the cell could use. At first, the cell encircled its food with its arms and then spat out the enzymes into the ocean water to break down its food outside the cell.

But this strategy was risky – sometimes the food floated away anyway before the cell could eat it. Successful cells began to encircle their prey completely with their arms to keep it from getting away. Then, about 2 billion years ago, a few eukaryote cells began to break off that bit of cell membrane and let it form a little bubble inside the main cell membrane, so that the food was inside the cell completely and the cell could eat it whenever it wanted to, or even store it for later. We call these bubbles vacuoles.

Once the food molecules were trapped inside the vacuoles, the cell could break the molecules apart to release the energy that held them together. Generally the part of the cell that began this process was the lysosome. Vacuoles got surrounded by the membrane of the lysosome, much the same way that the food originally got surrounded by the vacuole. Inside the lysosome there were powerful enzymes – molecules that could react with the food molecules to break them apart.

From the lysosome, these smaller molecules then moved to the mitochondria, where the mitochondria used other enzymes and oxygen to produce more chemical reactions to break up food molecules and release energy that the cell needed. This is how all eukaryote cells digest food even today, and it is how all the cells in your own body digest food. That’s why you need both food and oxygen – because your cells need to combine food and oxygen to break them down and make energy to keep your cells alive.

Learn by doing: a project with lipids
More about lysosomes
More about mitochondria
More about enzymes

Bibliography and further reading:

More about mitochondria
More about Cells
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